GLP-1s, peptides, HRT — the fastest-growing vertical in high-risk, and the most scrutinized. The file that clears shows licensed prescribers, a real telehealth consult before any charge, and pharmacy fulfillment you can document. LegitScript certification isn't mandatory everywhere, but it converts underwriters like nothing else.
Licensed telehealth with documented consults runs ~3.4–4.4%. Peptide-only sellers without prescriber flow price harder — fix the flow first.
Provider licenses by state, consult-before-charge flow, pharmacy agreements, and LegitScript (or a credible path to it).
Card networks fine processors for illegal pharma routing — so underwriters check your Rx chain, not your marketing. Make it checkable.